Anita Visan
Dr. Anita-Ioana VISAN
Scientific Researcher, 3rd degree

Experience and expertise:
• Nanopowders synthesis and characterization;
• Thin coatings of calcium phosphates, biopolymers, flavonoids, antibiotics,      antimicrobial peptides synthesized by: Pulsed Laser Deposition, Matrix          Assisted Pulsed Laser Evaporation, Combinatorial-MAPLE;
• Thin films characterization methods: UV-Vis , FTIR, XRD, SEM, AFM,              fluorescence microscopy, electrochemical, magnetic induction,                      biodegradation and antimicrobial tests.

email:
anita.visan@inflpr.ro
anita_ioana@yahoo.com

Work Experience

1

Scientific Researcher 3rd degree

Jun 2020 – present 
LSPI Laboratory, Lasers Department, INFLPR
2

Scientific Researcher

Dec. 2013 – Jun 2020
LSPI Laboratory, Lasers Department, INFLPR
3

Maternity leave

Jan.2017 – Sep. 2018
4

Research Assistant

Jun. 2007 – Nov. 2013
LSPI Laboratory, Lasers Department, INFLPR
5

Maternity leave

Sep. 2010 – Aug. 2012
6

Research Assistant Intern

Jan. 2007 – Jun. 2007
Research Assistant Intern, LSPI Laboratory, Lasers Department, INFLPR

Education

May 2015

PhD in Physics

University of Bucharest, Faculty of Physics, „Nanostructured thin films synthesized by advanced laser techniques for rapid healing and tissue regeneration”, Summa Cum Laude.

June 2009

MSc in Biomaterials

University POLITEHNICA of Bucharest, Faculty Materials Science and Engineering, grade of 10 (out of 10);                                                              

June 2007

BSc in Medical Engineering

University POLITEHNICA of Bucharest, Faculty Materials Science and Engineering, grade of 9.41 (out of 10), Valedictorian of Department of Medical Engineering

Honors and awards

  • National fellowship program 
    L’Oréal—UNESCO “For Women in Science” 2020.
  • Best Poster Award
    Vișan A.I. et al., EMRS 2014 Spring Meeting, Symposium J: Laser interaction with advanced materials: fundamentals and applications, May 26-30, 2014, Lille, France.
  • Best Oral Presentation
    Vișan A.I. et al., 5th International Student Conference on Photonics (ISCP’14), September 23-26, 2014, Orastie, Romania
  • Best Oral Presentation
    Vișan A.I. et al., INERA Workshop, September 4-6, 2014, Varna, Bulgaria

Working Stages

Oct - Nov 2015

French Government Scholarship at CIRIMAT Carnot Institute

Faculty of Pharmacy, Toulouse, France                                                                                                 

8 Apr - 1 May 2015

Applied Science Faculty

Chisinau, Moldova;                                                                                                          

26 Nov - 2 Dec 2012

Young researchers training in the field of nanotechnology and processing of functional materials Programme

Technological and Metallurgical Faculty, University of Belgrade, Belgrade,Serbia;                      

March - July 2009

University internship Erasmus

ENSIACET, Toulouse, France                                                                                                   

15-17 April 2008

Hidrosoluble Polymers for advanced applications

Institute of Macromolecular Chemistry Petru Poni, Iasi, Romania;                                                 

17-20 Sept 2008

Introduction to FTIR Technique

NILPRP, Bucuresti                                                                                                                 

5-10 Sept 2008

University of Marmara

Istanbul, Turkey                                                                                                                        

Research team member in international/national projects: 

  • Implant coatings based on low-cost sustainable natural resources for infection prevention (PN-III-P4-ID-PCE-2020-2273)
    Project Director (2021-2023)
  • DOC-3D-Printing (H2020 European Project): Development Of Ceramics 3D printing & Additive manufacturing 
    Key Expert (2018-2022)
  • PN-III-P4-ID-PCE-2016-0884 201: Innovative multifunctional nanoparticle-mediated delivery of antimicrobial peptide for improved performance of medical implants
    Key Expert (2017-2019)
  • PN-III-P3-3.1-PM-RO-BE-2016-0003: Biosensors functionalized by irradiation and transfer with laser pulses
    Key Expert (2016-2018)
  • PN-II-RU-TE-2014-4-0342: Surface acoustic wave sensors for H2S detection based on sensitive films with gradual porosity
    Key Expert (2015-2017)
  • PN-II-RU-TE-2014-4-1590: Controlled external activation of drug release from smart polymeric systems
    Key Expert (2015-2017)
  • ANR-13-IS09-0001: Innovative BIOmimetic nanostructured COATings for orthopaedic implants BY advanced pulsed LASER methods
    Key Expert (2014-2016)
  • 778/30.06.2014: Biomimetic nanocomposites obtained by advanced laser biotechnologies for rapid healing and regeneration of bone tissue
    Key Expert (2014-2016)
  • 153/2012/ PN-II-PT-PCCA-2011-3.2-0898: Manufacture of orthopedic implants with osteoinductive 3D gradually hierarchical structure
    Key Expert (2014-2016)
  • 209/2011/ PN-II-ID-PCE-2011-3-0888: Nanostructured and functionalized composite of flavonoid-biopolymer for antibacterial activity
    Key Expert (2014-2016)
  • PN-II-RU-TE-2010-0098:Nanostructures Processed By Laser Techniques For Photovoltaic Applications
    Key Expert (2014-2016)

Member of:

• Professional associations:
   - SPIE—The International Society for Optical Engineering;
   - Romanian Society of Biomaterials;
   - OSA Romanian Student Chapter - NILPRP–President (2015-2016).
• Local organizing committee of the 10th International Conference on Photoexcited Processes and Applications        (August 29 – September 2, 2016), Brasov, Romania (http://icpepa10.com/committees/). 

Reviewer for international journals

Journal of Physics D: Applied Physics; Applied Sciences; Materials; Sensors; Electronics; Coatings.

Topic Editor of journal 

Coatings (IF=2.436);

Guest Editor of Special Issue 

Polymers (IF=3.426): Polymeric Systems for Drug Delivery: From Synthesis to Applications 2020;
Polymers (IF=4.329): Polymer Applications in the Medical Field 2021;
Coatings (IF=2.881): Special Issue "Biomimetic Approaches in Coatings Synthesis"

Reviewer for international journals

Journal of Physics D: Applied Physics; Applied Sciences; Materials; Sensors; Electronics; Coatings.

Editorial/Reviewer Board Member 

Journal of Nanotechnology in Diagnosis and Treatment

Personal Skills

  • Known languages
    ▪ English (advanced level)
    ▪ French (medium level)
    ▪ Spanish (beginner level) 
  • Social skills and competences
    ▪High level of communication, acquired within the work teams of different research projects, following the national and international collaborations in which I was involved, at conferences and internships.
  • Technical skills and competences
    ▪Manipulation of laboratory installations (pulsed laser deposition systems, vacuum system);
    ▪Fabrication of thin films for medical applications. I have studied different biomaterials like:
  • -Pure or doped calcium phosphates: biomimetic hydroxyapatite; hydroxyapatite doped silver;
  • -Biopolymers: Polyethylene glycol; Polycaprolactone; chitosan; Poly(3-hydroxybutyric-acid-co-3-hydroxyvaleric-acid); poly(lactic-co-glycolic acid); polyaniline grafted lignin;
  • -Proteins: Lysozyme, Silk Fibroin; 
  • -Bacteries: Escherichia coli, Bacillus subtilis, Enterococcus faecalis and Staphylococcus aureus strains; 
  • -Antimicrobial: flavonoids; poly(1,3-bis-(p-carboxyphenoxy propane)-co-(sebacic anhydride)) /gentamicin sulfate;quercetin , Lignin, resveratrol.
  • -essential oils: aloe vera; incense, myrrh ;eucalyptus.
  • ▪Optical, structural and morphological characterizations of the obtained thin layers;
    ▪Writing scientific materials, in the form of: posters, manuscripts, research reports, research projects. 
  • Computer skills and competences
     CAD/CAM : Solid Works
  • MS Office: Word, Power Point, Excel;
  • Scientific data : Origin Lab;
  • Image processing : Image J
  • Other skills and competences
    ▪Organizational spirit in the daily activity in the laboratory, in the process of submitting national and international research projects and in the process of reporting the contracts won in the group;
  • ▪Financial and administrative evidence of the research projects in which I am involved;
    ▪Effectiveness and efficiency in critical situations 
  • Responsible with specialization stages:
  • Dépôt de bio-substances par technique LASER – application à l’apatite biomimétique par technique MAPLE (Matrix-Assisted Pulsed Laser Evaporation)- Erwan DANDEU, Polytech Lille, May - July, 2014;
  • Dépositions d’apatite biomimétique par la méthode MAPLE pour des applications médicales- Arthur RIVAL, Institut Universitaire de Technologie de Marseille, April 7th – June 20th, 2014.
  • Driving licence(s)
    ▪B category

Publications

2021

Composite Drug Delivery System Based on Amorphous Calcium Phosphate-Chitosan: An Efficient Antimicrobial Platform for Extended Release of Tetracycline
Visan A.I., Ristoscu C., Popescu-Pelin G., Sopronyi M., Matei C.E., Socol G., Chifiriuc M.C., Bleotu C., Grossin D., Brouillet F., Le Grill S., Bertrand G., Zgura I., Cristescu R., Mihailescu I.N.; PHARMACEUTICS; Volume 13; Issue 10;Article Number 1659; DOI 10.3390/pharmaceutics13101659; OCT 2021; IF2021 = 6.07; AIS2021 = 0.903


Degradation Behavior of Polymers Used as Coating Materials for Drug Delivery-A Basic Review 
Visan A.I., Popescu-Pelin G. and Socol G.; POLYMERS; Volume 13; Issue 8; Article Number 1272; DOI 10.3390/polym13081272; APR 2021; IF2021 = 4.329;
AIS2021 = 0.597

Artificial Neural Network Algorithms for 3D Printing 
Mahmood M.A., Visan A.I., Ristoscu C., Mihailescu I.N.; MATERIALS; Volume 14; Issue 1; Article Number 163; DOI 10.3390/ma14010163; JAN 2021;
IF2021 = 3.623; AIS2021 = 0.595

2020

Estimation of clad geometry and corresponding residual stress distribution in laser melting deposition: analytical modeling and experimental correlations
Mahmood M.A., Popescu A.C., Hapenciuc C.L., Ristoscu C., Visan A.I., Oane M. , Mihailescu I.N.; International Journal Of Advanced Manufacturing Technology; Volume 111; Issue 1-2; Page 77-91; DOI 10.1007/s00170-020-06047-6;NOV 2020; IF2020 = 3.226; AIS2020 = 0.471

Long-Term Evaluation of Dip-Coated PCL-Blend-PEG Coatings in Simulated Conditions
Visan A.I., Popescu-Pelin G., Gherasim ., Mihailescu A., Socol M., Zgura I ., Chiritoiu M., Sima L.E.,Antohe F., Ivan L., Vranceanu D.M. , Cotrut C.M., Cristescu R., Socol G.; POLYMERS; Volume 12; Issue 3; Article Number 717; DOI 10.3390/polym12030717; MAR 2020; IF2020 = 4.329; AIS2020 = 0.597

Matrix-Assisted Pulsed laser Evaporation-deposited Rapamycin Thin Films Maintain Antiproliferative Activity
Cristescu R., Negut I., Visan A.I., Nguyen A.K., Sachan A., Goering P.L., Chrisey D.B., Narayan R.J.; International Journal Of Bioprinting Volume 6; Issue 1 ; Page
105-111; Article Number 188; DOI 10.18063/ijb.v6i1.188; Published 2020 ;
IF2020 = 6.638; AIS2020 = 1.038

2019

Successful Release of Voriconazole and Flavonoids from MAPLE Deposited Bioactive Surfaces
Negut, I., Visan A.I., Popescu C., Cristescu R., Ficai A.,Grumezescu A.M., Chifiriuc M.C. Boehm R.D., Yamaleyeva D., Taylor M., Narayan R.J., Chrisey D.B.; APPLIED SCIENCES-BASEL; Volume 9; Issue 4; Article Number 786; DOI 10.3390/app9040786; FEB 2 2019; IF2019 = 2.679; AIS2019= 0.409

Laser Processed Antimicrobial Nanocomposite Based on Polyaniline Grafted Lignin Loaded with Gentamicin-Functionalized Magnetite
Visan, A.I.; Popescu-Pelin G., Gherasim O., Grumezescu V., Socol M., Zgura I., Florica C., Popescu R.C., Savu D., Holban A.M., Cristescu R., Matei C.E., Socol G., POLYMERS 11 (2) 283 (2019); IF2019= 3.426; AIS2019= 0.545

2017

Antimicrobial polycaprolactone/polyethylene glycol embedded lysozyme coatings of Ti implants for osteoblast functional properties in tissue engineering
Visan A.I.; Cristescu R., Stefan N., Miroiu M., Nita C., Socol M., Florica C., Rasoga O., Zgura I., Sima L.E., Chiritoiu M., Chifiriuc M.C., Holban A.M., Mihailescu I.N., Socol G.; Applied Surface Science 417, 234-243 (2017); IF2017 = 4.439;
AIS2017 = 0.627

Characterization of PLD grown WO3 thin films for gas sensing
Boyadjiev S.I., Georgieva V., Stefan N., Stan G.E., Mihailescu N., Visan A.I., Mihailescu I.N., Besleaga C., Szilagyi I.M.; (2017); Applied Surface Science; 417; 218-223;  IF2017 = 4.439; AIS2017 = 0.627

Printing amphotericin B on microneedles using matrix assisted pulsed laser evaporation
Sachan R., Jaipan P., Zhang J.Y., Degan S., Erdmann D., Tedesco J., Vanderwal L., Stafslien S.J., Negut I., Visan A.I., Dorcioman G., Socol G., Cristescu R., Chrisey D.B., Narayan R.J.; International Journal Of Bioprinting;   Volume: 3;   Issue: 2;  Pages: 147-157; 2017.

Characterization of MAPLE deposited WO3 thin films for electrochromic applications
Boyadjiev S. I., Stefan N., Mihailescu N., Visan A.I., Mihailescu I.N., Szilagyi I. M.;(2017); Journal of Physics: Conference Series 780 (1); 012013.

Influence of the liquid level and ablation process duration on the characteristics of nanostructures created by nanosecond laser ablation of Ag in water
Nikolov A.S., Nikov R.G., Nedyalkov N.N., Atanasov P.A., Alexandrov M.T., Karashanova D.B., Marinkov N.E., Dimitrov I.Z., Boevski I.I., Visan A.I., Mihailescu I.N.; (2017); Proceedings of SPIE; 2017; ISSN:0277-786X, DOI:10.1117/12.2262450 .

2016

Composite coatings based on renewable resources synthesized by advanced laser techniques
Chapter in “Composites from Renewable and Sustainable Materials”; Visan A.I., Ristoscu C., Mihailescu I. N.; InTech, ISBN 978-953-51-4956-9; 2016;
Edited by: Matheus Poletto

Combinatorial MAPLE deposition of antimicrobial orthopedic maps fabricated from chitosan and biomimetic apatite powders
Visan, A.I., Stan G.E., Ristoscu C., Popescu-Pelin G., Sopronyi M., Besleaga C., Luculescu C., Chifiriuc M.C., Hussien M.D., Marsan O., Kergourlay E., Grossin D., Brouillet F., Mihailescu I.N.; International Journal Of Pharmaceutics 511 (1); 505-515; (2016); IF2016 = 3.649 AIS2016 = 0.766

Antimicrobial activity of biopolymeric thin films containing flavonoid natural compounds and silver nanoparticles fabricated by MAPLE: A comparative study
Cristescu R., Visan, A.I., Socol G., Surdu, A.V., Oprea A.E., Grumezescu A.M., Chifiriuc M.C., Boehm R.D., Yamaleyeva D., Taylor M., Narayan R.J., Chrisey D.B.; Applied Surface Science 374; 290-296 (2016); IF2016 = 3.387 AIS2016 = 0.589

2015

Composite biodegradable biopolymer coatings of silk fibroin - Poly(3-hydroxybutyric-acid-co-3-hydroxyvaleric-acid) for biomedical applications
Miroiu F.M., Stefan N., Visan A.I., Nita C., Luculescu C.R., Rasoga O., Socol M., Zgura I., Cristescu R., Craciun D., Socol G.; Applied Surface Science 355; 1123-1131 (2015) IF2015 = 3.15 AIS2015 = 0.574

Microbial colonization of biopolymeric thin films containing natural compounds and antibiotics fabricated by MAPLE
Cristescu R., Surdu, A.V., Grumezescu A.M., Oprea A.E., Trusca R., Vasile O., Dorcioman G., Visan A.I., Socol G., Mihailescu I.N., Mihaiescu D., Enculescu M., Chifiriuc M.C., Boehm R.D., Narayan R.J., Chrisey D.B.; Applied Surface Science 336; 234-239 (2015) IF2015 = 3.15 AIS2015 = 0.574

Structural and biological evaluation of lignin addition to simple and silver-doped hydroxyapatite thin films synthesized by matrix-assisted pulsed laser evaporation
Jankovic A., Erakovic S., Ristoscu C., Mihailescu N., Duta L., Visan A.I., Stan G.E., Popa A.C., Husanu M.A., Luculescu C.R., Srdic V.V., Janackovic D., Miskovic-Stankovic V., Bleotu C., Chifiriuc M.C.; Mihailescu I.N.; Journal Of Materials Science-Materials In Medicine 26 (1); 17 (2015) IF2015 = 2.272 AIS2015 = 0.557

2014

Antifungal activity of Ag:hydroxyapatite thin films synthesized by pulsed laser deposition on Ti and Ti modified by TiO2 nanotubes substrates
Erakovic S., Jankovic A., Ristoscu C., Duta L., Serban N., Visan A.I., Mihailescu I.N., Stan G.E., Socol M., Iordache O., Dumitrescu I., Luculescu C.R., Janackovic D., Miskovic-Stankovic V., Applied Surface Science 293; 37-45 (2014)
IF2014 = 2.711 AIS2014 = 0.549

Biomimetic nanocrystalline apatite coatings synthesized by Matrix Assisted Pulsed Laser Evaporation for medical applications
Visan A.I., Grossin D., Stefan N., Duta L., Miroiu F.M., Stan G.E., Sopronyi M., Luculescu C., Freche M., Marsan O., Charvilat C., Ciuca S., Mihailescu I.N.; Materials Science And Engineering B-Advanced Functional Solid-State Materials 181; 56-63 (2014) IF2014 = 2.169 AIS2014 = 0.475

2013

Maple Deposition of Plga Micro- And Nanoparticles Embedded Into Polymeric Coatings
Socol G., Preda N., Socol M., Sima L., Luculescu C.R., Sima F., Miroiu M.,
Axente E., Visan A.I., Stefan N., Cristescu R., Dorcioman G., Stanculescu A., Radulescu L., Mihailescu I.N.; Digest Journal Of Nanomaterials And Biostructures 8 (2); 621-630 (2013) IF2013 = 1.123 AIS2013 = 0.209

2011

Deposition of antibacterial of poly(1,3-bis-(p-carboxyphenoxy propane)-co-(sebacic anhydride)) 20:80/gentamicin sulfate composite coatings by MAPLE
Cristescu R., Popescu C., Socol G., Visan A.I., Mihailescu I.N., Gittard S.D., Miller P.R., Martin T.N., Narayan R.J., Andronie A., Stamatin I., Chrisey D.B.; Applied Surface Science 257 (12); 5287-5292; (2011) IF2011 = 2.103 AIS2011 = 0.55

2010

Composite biocompatible hydroxyapatite-silk fibroin coatings for medical implants obtained by Matrix Assisted Pulsed Laser Evaporation
Miroiu F.M., Socol G., Visan A.I. Stefan N., Craciun D., Craciun V., Dorcioman G., Mihailescu I.N., Sima L.E., Petrescu S.M., Andronie A., Stamatin, I., Moga S.,
Ducu C., Materials Science And Engineering B-Advanced Functional Solid-State Materials 169 (43525); 151-158; (2010) IF2010 = 1.568 AIS2010 = 0.769