Affiliation
and official address:
Laser-Surface-Plasma Interactions laboratory, Lasers Department
National Institute for Lasers, Plasma and Radiation Physics - INFLPR
P.O. Box MG-36 RO-77125
Magurele, Bucharest, Romania
valentina.grumezescu@inflpr.ro
Place
of birth: Bucharest,
Romania
Nationality: Romanian
Education:
2018:
PhD diploma Politehnica University of
Bucharest, Doctoral School Applied
Chemistry and Materials Science; Department of Science and Engineering
of
Oxidic Materials and Nanomaterials. Diploma title „Nanostructured
Biomaterials”, the obtained qualificative: „Excellent”
2011 –
2013: MSc.
Politehnica University of Bucharest, Faculty of Applied Chemistry
and Materials Science; Department of Science and Engineering of Oxidic
Materials and Nanomaterials, Master: Micro and Nanomaterials, Master
thesis: "Ferromagnetic
Biomaterials".
2007 –
2011: BSc.
Politehnica University of Bucharest, Faculty of Applied Chemistry
and Materials Science.
July 2020 – present: Scientific Researcher III-rd degree at National Institute for Lasers, Plasma and Radiation Physics
January 2014 – June 2020: Scientific
Researcher
at National Institute for Lasers, Plasma and
Radiation Physics.
April
2013
– December
2013:
Research Assistant at National
Institute for Lasers, Plasma and Radiation Physics.
October
2012 –
March
2013: Junior Research Assistant at National
Institute for Lasers, Plasma and Radiation Physics.
January 2011 – present: Editorial Board - Biointerface Research in Applied Chemistry
January 2011 – present: Editorial Board - Letters in Applied NanoBioScience
2018
1. Grumezescu,
V.,
Negut, I., Grumezescu, A.M., Ficai, A., Dorcioman, G., Socol, G.,
Iordache, F.,
Trușcă, R., Vasile, B.S., Holban, A.M. MAPLE fabricated coatings based
on
magnetite nanoparticles embedded into biopolymeric spheres resistant to
microbial colonization. Applied Surface Science, 448, 230-236, 2018. IF = 5.155
2. Negut, I., Grumezescu,
V., Ficai, A.,
Grumezescu, A.M., Holban, A.M., Popescu, R.C., Savu, D., Vasile, B.S.,
Socol,
G. MAPLE deposition of Nigella sativa functionalized
Fe3O4 nanoparticles for antimicrobial coatings.
Applied
Surface Science, 455, 513–521, 2018. IF
= 5.155
3. Popescu-Pelin, G. Fufă, O.
Popescu, R.C., Savu, D., Socol, M., Zgură, I., Holban, A.M., Vasile,
B.Ş., Grumezescu, V., Socol, G.
Lincomycin–embedded PANI–based coatings for biomedical
applications. Applied
Surface Science, 455, 653-666, 2018. IF = 5.155
4. Ficai, D.,
Grumezescu,
V., Fufă, O.M.,
Popescu, R.C., Holban, A.M.,
Ficai, A., Grumezescu, A.M., Mogoanta, L.,
Mogosanu, G.D., Andronescu, E.
Antibiofilm coatings based on PLGA and nanostructured
cefepime-functionalized
magnetite. Nanomaterials, 8(9), 633, 2018. IF
= 4.034
5. Negut, I.,
Grumezescu,
V., Grumezescu, A.M. Treatment
strategies for infected wounds. Molecules, 23(9), 2392, 2018. IF = 3.060
1. Grumezescu,
V.; Holban, A.M.; Sima, L.E.; Chiritoiu, M.B.; Chiritoiu, G.N.; Grumezescu, A.M.; Ivan, L.; Safciuc, F.; Antohe, F.; Florica, C.; Luculescu, C.R.; Chifiriuc, M.C.; Socol, G. Laser
deposition of poly(3-hydroxybutyric acid-co-3-hydroxyvaleric acid) -
lysozyme
microspheres based coatings with anti-microbial properties.
International
Journal Of Pharmaceutics, 521(1-2), 184-195, 2017 . IF
= 3.862
2.
Curutiu, C., Grumezescu,
V., Chifiriuc, M.C., Huang, K.-S., Iordache, F., Lin, Y.-M.,
Holban,
A.M. Nanostructured approaches for the targeted delivery of antibiotics
in
difficult infections. Current Organic Chemistry, 21(1), 45-52, 2017. IF = 2.193
3.
Rașoga, O., Sima, L., Chirițoiu, M., Popescu-Pelin, G.,
Fufă, O., Grumezescu, V.,
Socol, M., Stănculescu, A., Zgură, I., Socol, G. Biocomposite coatings
based on
poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/calcium phosphates
obtained by
MAPLE for bone tissue engineering. Applied Surface Science, 417,
204-212, 2017. IF =
4.439
2016
1.
Oprea, A.E., Pandel, L.M., Dumitrescu, A.M., Andronescu, E., Grumezescu,
V., Chifiriuc, M.C., Mogoantă,
L., Bălşeanu,
T.-A.,
Mogoşanu, G.D., Socol, G., Grumezescu, A.M., Iordache, F., Maniu, H.,
Chirea,
M., Holban, A.M. Bioactive ZnO coatings deposited by
MAPLE - An appropriate strategy to produce efficient anti-biofilm
surfaces, Molecules 21(2), 220, 2016. IF
= 2.861
2.
Bjelajac, A., Petrovic, R., Socol, G., Mihailescu, I.N., Enculescu,
M., Grumezescu, V., Pavlovic, V.,
Janackovic, D. CdS quantum dots sensitized
TiO2
nanotubes by matrix assisted pulsed laser evaporation method. Ceramics
International, 42(7), 9011-9017, 2016. IF
= 2.986
3.
Rădulescu, D., Voicu, G., Oprea, A.E., Andronescu, E., Grumezescu,
V., Holban, A.M., Vasile, B.S., Surdu, A.V., Grumezescu, A.M.,
Socol, G.,
Mogoantă,
L., Mogoşanu, G.D.,
Balaure, P.C., RǍdulescu,
R., Chifiriuc,
M.C. Mesoporous silica coatings for cephalosporin active release at the
bone-implant interface. Applied Surface Science, 374, 165-171, 2016. IF = 3.387
4.
Rădulescu, D., Grumezescu, V.,
Andronescu, E., Holban, A.M.,
Grumezescu, A.M., Socol, G., Oprea, A.E., Rădulescu,
M., Surdu, A., Trusca, R., Rădulescu,
R., Chifiriuc,
M.C., Stan, M.S., Constanda, S., Dinischiotu, A. Biocompatible
cephalosporin-hydroxyapatite-poly(lactic-co-glycolic
acid)-coatings fabricated by MAPLE technique for the prevention of bone
implant
associated infections. Applied Surface Science, 374, 387-396, 2016. IF = 3.387
5.
Stan, M.S., Constanda, S., Grumezescu, V.,
Andronescu, E., Ene,
A.M., Holban, A.M., Vasile, B.S., Mogoantă,
L., Bălşeanu,
T.-A., Mogoşanu, G.D.,
Socol, G., Grumezescu, A.M., Dinischiotu, A., Lazar, V., Chifiriuc,
M.C. Thin
coatings based on ZnO@C18-usnic acid nanoparticles prepared by MAPLE
inhibit
the development of Salmonella
enterica early
biofilm growth. Applied Surface Science, 374, 318-325, 2016. IF = 3.387
6.
Socol, M., Preda, N., Rasoga, O., Breazu, C., Stavarache, I.,
Stanculescu, F., Socol, G., Gherendi, F., Grumezescu,
V., Popescu-Pelin,
G., Girtan, M., Stefan, N. Flexible heterostructures based on metal
phthalocyanines thin films obtained by MAPLE. Applied Surface Science,
374,
403-410, 2016. IF = 3.387
7. Holban A.M., Vlad M., Grumezescu
V., Ficai A., Bleotu C., Aldea (Pitica) I.M., Grumezescu A.M.,
Andronescu
E. Impact Of Alginate On The Biocompatibility Of Magnetite
Nanoparticles
Utilized For Drug Delivery. U.P.B. Sci. Bull., Series B, 78(4), ISSN
1454-2331,
2016.
8. Holban,
A.M., Grumezescu, V., Ficai, A., Grumezescu, A.M., Chifiriuc, M.C., Iordache, F.,
Andronescu, E. Highly
biocompatible magnetite nanoparticles
functionalized with chitosan for improving the efficiency of antibiotics. U.P.B. Sci. Bull., Series B, 78(3), 47-58, 2016.
2015
1.
Holban, A.M., Andronescu, E., Grumezescu,
V., Oprea, A.E., Grumezescu, A.M., Socol, G., Chifiriuc, M.C.,
Lazar, V.,
Iordache, F. Carvone functionalized iron oxide nanostructures thin
films
prepared by MAPLE for improved resistance to microbial colonization.
Journal of
Sol-Gel Science and Technology, 73(3), 605-611, 2015. IF = 1.473
2.
Grumezescu, A.M., Andronescu, E., Oprea, A.E., Holban, A.M.,
Socol, G., Grumezescu, V., Chifiriuc, M.C., Iordache,
F., Maniu,
H. MAPLE fabricated magnetite@Melissa
officinalis and poly lactic acid –
chitosan coated surfaces with anti-staphylococcal properties. Journal
of
Sol-Gel Science and Technology, 73(3), 612-619, 2015. IF = 1.473
3.
Grumezescu
V.,
Andronescu E.,
Holban A.M.,
Mogoantă L., Mogoșanu G.D.,
Grumezescu A.M.,
Stănculescu A., Socol G., Iordache F., Maniu H., Chifiriuc C.M. MAPLE
fabrication of
thin films based on kanamycin functionalized magnetite nanoparticles
with
anti-pathogenic properties.
Applied
Surface Science, 336, 188-195, 2015. IF =
3.150
4.
Grumezescu V.; Andronescu E.; Holban A.M.; Socol G.;
Grumezescu A.; Ficai A.; Lazar V.; Chifiriuc C.M.; Trusca R.; Iordache
F. Fabrication
and characterization of functionalized surfaces with 3-amino
propyltrimethoxysilane
films for anti-infective therapy applications. Applied
Surface Science, 336, 401-406, 2015. IF =
3.150
5.
Iordache
F.; Grumezescu
V.; Grumezescu A.; Curuțiu C.; Dițu L.M.; Socol G.; Ficai A.;
Trusca
R.; Holban A.M. Gamma-cyclodextrin/usnic
acid thin
film fabricated by MAPLE for improving the resistance of medical
surfaces to
Staphylococcus aureus colonization. Applied
Surface Science, 336, 407-4121, 2015. IF =
3.150
6.
Iordache F., Oprea A.E., Grumezescu V., Andronescu E.,
Socol G., Grumezescu A.M., Popa M., Mogoșanu G.D., Holban A.M., Maniu
H. Poly(lactic-co-glycolic)
acid/chitosan microsphere thin films functionalized with Cinnamomi aetheroleum
and magnetite nanoparticles for preventing the microbial
colonization of
medical surfaces. Journal of Sol-Gel Science and Technology, 73(3),
679-686,
2015. IF = 1.473
2014
1.
Grumezescu A.M., Ghitulica, C.D., Voicu, G., Huang, K.S.,
Yang, C.H., Ficai, A., Vasile, B.S., Grumezescu,
V., Bleotu, C., Chifiriuc, C.M. New
silica nanostructure for the improved delivery of topical antibiotics
used in
the treatment of staphylococcal cutaneous infections. International
Journal of Pharmaceutics, 463, 170–176, 2014. IF = 3.650
2. Grumezescu, V., Socol, G., Grumezescu, A.M., Holban, A.M., Ficai, A., Trusca, R., Bleotu, C., Balaure, P.C., Cristescu, R., Chifiriuc, M.C. Functionalized antibiofilm thin coatings based on PLA-PVA microspheres loaded with usnic acid natural compounds fabricated by MAPLE. Applied Surface Science, 302, 262–267, 2014. IF = 2.711
3.
Grumezescu,
V.;
Holban, A.M.;
Iordache, F.; Socol, G.; Mogosanu, G.D.;
Grumezescu, A.M.; Ficai, A.; Vasile, B.S.; Trușcă, R.;
Chifiriuc, C.M.;
Maniu, H. MAPLE fabricated magnetite@eugenol and
(3-hidroxybutyric
acid-co-3-hidroxyvaleric acid) – polyvinyl alcohol microspheres
coated surfaces
with anti-microbial properties. Applied
Surface Science, 306,
16-22
2014. IF = 2.711
5.
Grumezescu,
V.,
Holban, A.M., Grumezescu,
A.M., Socol, G., Ficai, A., Vasile, B.S.,
Trusca, R., Bleotu, C., Lazar, V., Chifiriuc, C.M., Mogosanu, G.D.
Usnic
acid loaded biocompatible magnetic PLGA-PVA microspheres thin films
fabricated
by MAPLE with increased resistance to staphylococcal colonization.
Biofabrication, 6, 035002, 2014. IF = 4.289
6.
Bertesteanu, S.,
Chifiriuc, M.C.,
Grumezescu, A.M.,
Printza Α.G., Thill, M.P., Grumezescu,
V., Vlad, M., Lazar, V., Grigore, R. Biomedical Applications of
Synthetic, Biodegradable Polymers for the Development of Anti-Infective
Strategies. Current
Medicinal Chemistry, 21(29), 3383-90, 2014. IF = 3.853
7.
Grumezescu,
A.M.,
Gestal, M.C., Holban, A.M., Grumezescu, V.,
Vasile, B.Ș., Mogoantă, L.,
Iordache, F., Bleotu, C., Mogoșanu, G.D. Biocompatible Fe3O4
increases the efficacy of amoxicillin delivery against
Gram-positive and
Gram-negative bacteria. Molecules,
19,
5013-5027,
2014. IF =
2.416
8.
Holban,
A.M., Grumezescu,
V.,
Grumezescu, A.M.,
Vasile B.Ș., Trușcă R., Cristescu, R., Socol, G., Iordache,
F. Anti-microbial
nanospheres thin coatings prepared by advanced pulsed laser
technique.
Beilstein Journal
of Nanotechnology, 5,
872–880, 2014.
IF = 2.670
9.
Anghel,
A.G.; Grumezescu, A.M.; Chirea, M.; Grumezescu, V.;
Socol, G.;
Iordache, F.; Oprea, A.E.; Anghel, I.; Holban, A.M. MAPLE fabricated
Fe3O4@Cinnamomum verum
antimicrobial surfaces for improved gastrostomy tubes. Molecules,
19,
8981-8994, 2014. IF = 2.416
10.
Limban, C., Missir, A.V.,
Grumezescu, A.M., Oprea, A.E., Grumezescu, V.,
Vasile, B.Ș.,
Socol, G., Trușcă, R., Caproiu, M.T., Chifiriuc, M.C., Gălățeanu, B.,
Costache,
M., Morușciag, L., Pîrcălăbioru, G., Nuță, D.C. Bioevaluation of
novel
anti-biofilm coatings based on PVP/Fe3O4
nanostructures and 2-((4-ethylphenoxy)methyl)-N-(arylcarbamothioyl)benzamides.
Molecules, 19, 12011-12030, 2014. IF = 2.416
11.
Holban A.M., Andronescu E., Grumezescu V., Socol G.,
Grumezescu A.M., Lazăr V., Chifiriuc M.C. Local delivery of
tetracycline from
gamma-aminobutiric acid-silica networks thin films for preventing
microbial
colonization. Biomaterials and Tissue Engineering Bulletin, 1(1-4),
2-9, 2014.
2013
1.
Voicu, G., Grumezescu, V., Andronescu, E.,
Grumezescu, A.M., Ficai, A., Ghitulica, C.D., Gheorghe, I., Chifiriuc,
M.C. Caprolactam-silica
network, a strong potentiator of the antimicrobial activity of
kanamycin
against Gram-positive and Gram-negative bacterial strains.
International
Journal of Pharmaceutics, 446,
1–2,
63-69, 2013. IF =
3.785
2. Grumezescu,
V.,
Chifiriuc, C.M., Holban, A.M., Stoica, P.,
Grumezescu, A.M., Voicu, G., Socol, G., Huang, K.S., Bleotu, C.,
Radulescu,
R. Antimicrobial And Biocompatibility Assay Of Newly
Fabricated Materials Based Copper Or
Zinc Alginate And SiO2 Network. Digest
Journal of Nanomaterials and Biostructures, 8,
2, 869 – 876, 2013. IF = 1.123
3. Grumezescu,
A.M., Andronescu, E., Ficai, A., Grumezescu, V.,
Bleotu, C.,
Saviuc, C., Mihaiescu, D.E., Chifiriuc, C.M. Biocompatible
Magnetic
Hollow Silica Microspheres for Drug Delivery. Current Organic
Chemistry, 17, 1029-1033, 2013. IF = 2.537
4.
Chifiriuc,
M.C., Grumezescu, A.M., Saviuc, C.,
Hristu, R., Grumezescu, V.,
Bleotu, C., Stanciu, G., Mihaiescu, D.E., Andronescu, E., Lazar, V.,
Radulescu,
R. Magnetic Nanoparticles for Controlling in vitro Fungal
Biofilms. Current Organic Chemistry, 17, 1023-1028, 2013. IF
= 2.537
5. Chifiriuc,
M.C., Grumezescu, A.M., Andronescu, E., Ficai, A.,
Cotar, A.I., Grumezescu, V.,
Bezirtzoglou, E., Lazar, V., Radulescu, R. Water dispersible magnetite
nanoparticles influence the efficacy of antibiotics against planktonic
and biofilm
embedded Enterococcus faecalis
cells. Anaerobe, 22,
14-19,
2013. IF = 2.364
6. Grumezescu,
A.M., Cotar, A.I., Andronescu, E., Ficai, A.,
Ghitulica, C.D., Grumezescu, V.,
Vasile, B.S., Chifiriuc, M.C. In vitro
activity of the new water dispersible Fe3O4@Usnic
Acid
nanostructure against planktonic and sessile bacterial cells. Journal
of
Nanoparticle Research, 15,
1766,
2013. IF = 2.278
7. Grumezescu,
A.M., Andronescu, E., Holban, A.M., Ficai, A., Ficai, D., Voicu, G., Grumezescu, V., Balaure, P.C.,
Chifiriuc, C.M. Water
dispersible cross-linked
magnetic chitosan beads for increasing the antimicrobial efficiency of
different therapeutic agents.
International
Journal of Pharmaceutics, 454, 233-240,
2013. IF = 3.785
2012
1.
Chifiriuc, C., Grumezescu,
V., Grumezescu, A.M., Saviuc, C., Lazǎr, V., Andronescu, E.
Hybrid
magnetite nanoparticles/rosmarinus
officinalis essential oil nanobiosystem with
antibiofilm activity. Nanoscale Research Letters, 7, 209,
2012.
IF = 2.524
2. Anghel,
I., Grumezescu,
V., Andronescu, E., Anghel, G.A., Grumezescu, A.M., Mihaiescu,
D.E.,
Chifiriuc, M.C. Protective effect of magnetite nanoparticle/Salvia officinalis
essential oil hybrid nanobiosystem against fungal colonization on the
provox®
voice section prosthesis. Digest Journal of Nanomaterials and
Biostructures, 7
(3), 1205-1212, 2012. IF = 1.092
3. Anghel,
I., Grumezescu, A.M., Andronescu, E., Anghel, A.G., Ficai,
A., Saviuc, C., Grumezescu, V.,
Vasile, B.S., Chifiriuc, M.C. Magnetite nanoparticles for
functionalized
textile dressing to prevent fungal biofilms development. Nanoscale
Research
Letters, 7, 501, 2012. IF = 2.524
4. Grumezescu,
A.M., Chifiriuc, M.C., Saviuc, C., Grumezescu, V.,
Hristu, R.,
Mihaiescu, D.E., Stanciu, G.A., Andronescu, E. Hybrid nanomaterial for
stabilizing the antibiofilm activity of eugenia
carryophyllata essential oil. IEEE Transactions on Nanobioscience,
11 (4),
6290401, 360-365, 2012. IF = 1.286
6. Negut,
I., Grumezescu
V., Sima, L.E., Axente, E. Chapter 11 - Recent advances of
graphene
family nanomaterials for nanomedicine. Book: Fullerens, Graphenes and
Nanotubes, Elsevier
Inc., 413-455,
2018. ISBN:
978-0-12-813691-1
5.
Negut, I., Grumezescu,
V., Dorcioman, G. Chapter 6: Progress of nanoparticles research
in
cancer therapy and diagnosis. Book: Nanostructures for Cancer Therapy, Elsevier
Inc., 159-176
2017.
ISBN:
978-0-323-46144-3
4. Negut,
I., Grumezescu,
V., Dorcioman, G., Socol, G. Chapter 1: Microscale Drug
Delivery
Systems: Current Perspectives and Novel Approaches. Book: Nano- and
Microscale
Drug Delivery Systems, Elsevier
Inc., 1-15,
2017.
ISBN: 978-0-323-52727-9
2. Grumezescu V., Holban A.M.,
Barbu I., Popescu R.C., Oprea A.E., Lazar V., Grumezescu A.M.,
Chifiriuc M.C. Chapter
7: Nanoarchitectonics used
in antiinfective therapy. Book: Antibiotic
Resistance, Elsevier Inc., 2016.
ISBN: 978-0-12-803642-6
1.
Grumezescu
A.M., Holban A.M., Ficai A., Grumezescu
V., Lazar V., Chifiriuc M.C. Biotechnology – Volume X:
Nanobioctechnology, Nanosized Materials with Antibiofilm Activity,
Studium
Press LLC, Houston, USA, 2014. ISBN: 1-62699-025-5