The transfer by two laser methods of four different types of protein biomolecules is proposed with the aim to improve the osseointegration of biomimetic implants previously coated with a nanometric layer of calcium phosphate also deposited by laser. The main objective of this project is to cover calcium phosphate nanostructured coatings obtained by Pulsed Laser Deposition on substrates of biomedical interest with protein multistructures/multilayers or micropatterns by Matrix-Assisted Pulsed Laser Evaporation. Biochemical assays will be corroborated with physicochemical analyses, expecting a relevant feedback in developing and improving the description of FTIR or wettability investigations after the biochemical evaluation of the coatings. Finally, in vitro tests will verify the functionality of the laser-transferred molecules versus bone marrow-derived cells.